Exercise-Induced Changes in Degenerative Mitral Regurgitation

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Exercise-induced changes in degenerative mitral regurgitation.

OBJECTIVES We sought to quantify exercise-induced changes in patients with degenerative mitral regurgitation (MR), to examine the relationship between exercise-induced changes in MR and in systolic pulmonary artery pressure (PAP), and to identify their potential impact on symptom-free survival. BACKGROUND MR severity can change during exercise in patients with functional MR. Quantified change...

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Imaging Exercise Pulmonary Hypertension in Asymptomatic Degenerative Mitral Regurgitation

Background—Current guidelines recommend mitral valve surgery for asymptomatic patients with severe degenerative mitral regurgitation and preserved left ventricular systolic function when exercise pulmonary hypertension (PHT) is present. However, the determinants of exercise PHT have not been evaluated. The aim of this study was to identify the echocardiographic predictors of exercise PHT and th...

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Exercise Pulmonary Hypertension in Asymptomatic Degenerative Mitral Regurgitation

Background—Current guidelines recommend mitral valve surgery for asymptomatic patients with severe degenerative mitral regurgitation and preserved left ventricular systolic function when exercise pulmonary hypertension (PHT) is present. However, the determinants of exercise PHT have not been evaluated. The aim of this study was to identify the echocardiographic predictors of exercise PHT and th...

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Prediction of exercise pulmonary hypertension in asymptomatic degenerative mitral regurgitation.

OBJECTIVE Exercise systolic pulmonary arterial pressure (SPAP) predicts the occurrence of symptoms in patients with degenerative mitral regurgitation (MR). However, this measurement is not always available. The purpose of this study was to identify resting echocardiographic predictors of exercise SPAP and whether predicted exercise SPAP may predict symptom-free survival. METHODS We prospectiv...

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Prognostic significance of exercise-induced right ventricular dysfunction in asymptomatic degenerative mitral regurgitation.

BACKGROUND The role of exercise-induced pulmonary hypertension in decision making regarding surgical timing for asymptomatic chronic mitral regurgitation is controversial. We reasoned that the exercise-induced pulmonary hypertension response could not be interpreted without knowledge of right ventricular (RV) function. The aim of this study was to assess the role of RV measures at rest and duri...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2010

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2009.12.073